Higher Scientific Officer, Biology – Centre for Protein Degradation For The Institute of Cancer Research

Full time
Posted 4 weeks ago

Job description

Salary: Commencement on the salary range is subject to comparable skills and experience. Future progression is based on annual performance review.

This role is eligible for ICR Sponsorship. Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here.

Duration of Contract: Fixed Term for 2 years (in first instance)

Hours per week: 35 hours per week (Full Time)

Closing Date16th July 2024

Location: Onsite, Sutton

Job Details

We are seeking to appoint a Higher Scientific Officer within the Centre for Protein Degradation to deliver biology aspects of the Centre’s projects. The post holder will use state of the art chemical biology techniques and cellular screening to explore the mechanism of action of small molecule degraders, and will work with others to develop novel reagents, cellular assays, and proteomic methods. The Centre for Protein Degradation is a multidisciplinary team, and this position will involve collaborative working with colleagues in chemistry, structural biology, DMPK and computational chemistry to develop biochemical and cell-based assays for testing and validating protein degraders and novel anticancer targets for TPD drug discovery programs.

Key Requirements

The successful candidate must have a first degree in a biological/physical science, knowledge of cell/cancer biology, and expertise in cellular/molecular biology and biochemistry techniques required to deliver biology aspects of the Centre’s projects. They must also have strong intellectual curiosity and commitment to successfully learn new research methodologies, as well as the ability to work productively with others as part of a large, multidisciplinary team.

Department/Directorate Information

Scientists in the Centre for Cancer Drug Discovery implement innovative drug discovery technologies, discover novel mechanism-based drugs, and develop these as rapidly as possible from the laboratory through to hypothesis-testing early clinical trials. We publish our work extensively and have a large network of collaborations with academia, biotechnology companies, and the pharmaceutical industry. Our drug discovery Biology teams are dedicated to translational and drug discovery research, applying molecular pharmacology and cancer biology approaches to explore the therapeutic potential of new targets, and implementing functional and mechanistic assays to support progression of new small molecule therapeutics.

Based within the ICR Centre for Cancer Drug Discovery, the Centre for Protein Degradation’s scientists apply a wide range of protein degradation technologies to benefit fundamental discovery science and translational research across the ICR. This research provides a nucleus for other teams to collaborate with, bringing their specialist biological and clinical knowledge to enable the exploration of therapeutic protein degradation for cancer patient benefit.

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Prof. Zoran Rankovic, Director of the Centre for Protein Degradation via email on [email protected].

About The Institute of Cancer Research

Why work for us?

As a member of staff, you’ll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.Report job

Job Features

Job CategoryPharmaceutical & Biotechnology

Apply Online